Food‐induced thyrotoxicosis in a dog

Abstract This report presents a case of factitial thyrotoxicosis in a dog ensuing from the long‐term administration of a raw meat‐based pet food adulterated with thyroid tissue. A 7‐year‐old, male, neutered bull terrier was brought to the clinic because of polyuria/polydipsia, restlessness and a decrease in bodyweight despite increased appetite. Physical examination revealed hyperthermia, polypnea, tachycardia and a mild underconditioning, whereas routine bloodwork and urinalysis were unremarkable. Exogenous thyrotoxicosis was suspected based on thyroid function test results, together with contrast computed tomography and nuclear scintigraphy of the thyroid gland, showing increased serum T4 concentrations and very low thyroid‐stimulating hormone concentration in the absence of either eutopic or ectopic thyroid tumours. Histological and biomedical analyses of the dog's diet identified it to be the likely source of environmental thyroid hormones. Diagnosis confirmation was achieved by transitioning the dog to a new food, which was accompanied by a speedy and full remission of clinical signs.

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Publication Details

Journal
Veterinary Record Case Reports
Published
2024-08-25
DOI
https://doi.org/10.1002/vrc2.975
Citations
2
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.72
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article

Food‐induced thyrotoxicosis in a dog

Ronald Jan Corbee, Marco Isidori, H.S. Kooistra
2 citations
Veterinary Record Case Reports
Thyroid Disorders and Treatments
0.72
article

Food‐induced thyrotoxicosis in a dog

Ronald Jan Corbee, Marco Isidori, H.S. Kooistra
article en
2 citations

Abstract

Abstract This report presents a case of factitial thyrotoxicosis in a dog ensuing from the long‐term administration of a raw meat‐based pet food adulterated with thyroid tissue. A 7‐year‐old, male, neutered bull terrier was brought to the clinic because of polyuria/polydipsia, restlessness and a decrease in bodyweight despite increased appetite. Physical examination revealed hyperthermia, polypnea, tachycardia and a mild underconditioning, whereas routine bloodwork and urinalysis were unremarkable. Exogenous thyrotoxicosis was suspected based on thyroid function test results, together with contrast computed tomography and nuclear scintigraphy of the thyroid gland, showing increased serum T4 concentrations and very low thyroid‐stimulating hormone concentration in the absence of either eutopic or ectopic thyroid tumours. Histological and biomedical analyses of the dog's diet identified it to be the likely source of environmental thyroid hormones. Diagnosis confirmation was achieved by transitioning the dog to a new food, which was accompanied by a speedy and full remission of clinical signs.

Veterinary Record Case ReportsVol. 12(4)
University of Padua (IT), University of Applied Sciences Utrecht (NL), Utrecht University (NL), Veterinary Oncological Center (IT)
Openalex Percentile: Top 26%
Thyroid Disorders and Treatments
0.72
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