Crohn's Disease, Hemochromatosis, Hepatocellular Carcinoma, and Liver Cirrhosis: A Case Study

Hemochromatosis, an inherited disorder characterized by excessive iron absorption and accumulation, can lead to organ damage and is a known contributor to liver cirrhosis. This case report discusses a 57-year-old man with a history of Crohn's disease, whose general practitioner identified elevated ferritin levels, cirrhotic liver features, and abnormal liver function tests. Further investigation revealed non-hereditary hemochromatosis, hepatic cirrhosis, and hepatocellular carcinoma (HCC). This case highlights the rare coexistence of hemochromatosis and Crohn's disease, underscoring the diagnostic and therapeutic challenges of managing these concurrent conditions. It also emphasizes the importance of prompt and effective treatment to prevent severe complications.

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Publication Details

Journal
Cureus
Published
2024-08-26
DOI
https://doi.org/10.7759/cureus.67781
Primary Topic
Iron Metabolism and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Crohn's Disease, Hemochromatosis, Hepatocellular Carcinoma, and Liver Cirrhosis: A Case Study

Ali Abdel Raheem, S Sankar, Noim Jibon, Dalia Alrawashdeh et al.
Cureus
Iron Metabolism and Disorders
article

Crohn's Disease, Hemochromatosis, Hepatocellular Carcinoma, and Liver Cirrhosis: A Case Study

Ali Abdel Raheem, S Sankar, Noim Jibon, Dalia Alrawashdeh, Vinod Warrier
article en

Abstract

Hemochromatosis, an inherited disorder characterized by excessive iron absorption and accumulation, can lead to organ damage and is a known contributor to liver cirrhosis. This case report discusses a 57-year-old man with a history of Crohn's disease, whose general practitioner identified elevated ferritin levels, cirrhotic liver features, and abnormal liver function tests. Further investigation revealed non-hereditary hemochromatosis, hepatic cirrhosis, and hepatocellular carcinoma (HCC). This case highlights the rare coexistence of hemochromatosis and Crohn's disease, underscoring the diagnostic and therapeutic challenges of managing these concurrent conditions. It also emphasizes the importance of prompt and effective treatment to prevent severe complications.

CureusVol. 16(8)
Southend University Hospital NHS Foundation Trust (GB)
Good health and well-being
Openalex Percentile: Top 79%
Iron Metabolism and Disorders
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