Simultaneous detection of membrane protein and mRNA at single extracellular vesicle level by droplet microfluidics for cancer diagnosis
Consequently, this study proposes a promising strategy for accurately identifying and analyzing specific EV subgroups through the co-detection of proteins and mRNA at the single EV level, holding significant potential for future clinical applications.
Authors
- Weilun Pan (ORCID: https://orcid.org/0000-0002-2119-5033)
- Mingzhen Zhong
- Xiaohui Yan (ORCID: https://orcid.org/0000-0003-2114-8357)
- Bodeng Wu (ORCID: https://orcid.org/0009-0008-6262-9142)
- Jingyun Guo (ORCID: https://orcid.org/0000-0002-7827-9123)
- Bo Situ (ORCID: https://orcid.org/0000-0002-4623-9530)
- Lei Zheng (ORCID: https://orcid.org/0000-0003-2576-8780)
- Xueying Mai
- Chunchen Liu (ORCID: https://orcid.org/0000-0002-5830-1805)
- Bo Li (ORCID: https://orcid.org/0000-0002-7979-8339)
- Yifan Liu (ORCID: https://orcid.org/0000-0002-2989-6280)
- Wei Liu (ORCID: https://orcid.org/0000-0003-4789-362X)
- Ye Zhang (ORCID: https://orcid.org/0000-0001-6159-7427)
- Haiyang Yu
- Tong Liao
- Huixian Lin
Institutions
- ShanghaiTech University (CN)
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1016/j.jare.2024.08.026
- Citations
- 20
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 4.68
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China
- National Science Fund for Distinguished Young Scholars
- Basic and Applied Basic Research Foundation of Guangdong Province