A Supramolecular Fluorescent Sensor Array Composed of Conjugated Fluorophores and Cucurbit[7]uril for Bacterial Recognition

Bacterial infections have emerged as a significant contributor to global mortality and morbidity rates. Herein, we introduce a dual fluorescence "turn-on" supramolecular sensor array composed of three assembled complexes (<b>C1</b>-<b>C3</b>), formed from three positively charged fluorophores (<b>A1</b>-<b>A3</b>) and one cucurbit[7]uril (CB[7]). The ability of this three-element array to simultaneously recognize 10 bacterial species within just 30 s was remarkable, boasting an impressive 100% accuracy. Additionally, the array excelled at distinguishing among various bacterial mixtures and enabled the quantitative detection of common bacterial strains. Notably, it has been skillfully applied to differentiate 10 bacterial samples in urine, achieving excellent differentiation and showcasing promising potential for medical diagnostic applications.

Authors

Institutions

Publication Details

Journal
Analytical Chemistry
Published
2024-08-26
DOI
https://doi.org/10.1021/acs.analchem.4c02625
Citations
22
Primary Topic
Luminescence and Fluorescent Materials
Type
article
Field-Weighted Citation Impact
2.58

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A Supramolecular Fluorescent Sensor Array Composed of Conjugated Fluorophores and Cucurbit[7]uril for Bacterial Recognition

Shujun Jiang, Weiwei Ni, M. Q. Liu, Fei Li et al.
22 citations
Analytical Chemistry
Luminescence and Fluorescent Materials
2.58
article

A Supramolecular Fluorescent Sensor Array Composed of Conjugated Fluorophores and Cucurbit[7]uril for Bacterial Recognition

Shujun Jiang, Weiwei Ni, M. Q. Liu, Fei Li, Zhijun Zhang, Meng Zhang, Hui Huang, Jinsong Han, Yanliang Zhang, Yang Yu, Huihai Li, Ying Bian, Mingqi Cheng, Weijia Chen, Xiao Shi
article en
22 citations

Abstract

Bacterial infections have emerged as a significant contributor to global mortality and morbidity rates. Herein, we introduce a dual fluorescence "turn-on" supramolecular sensor array composed of three assembled complexes (<b>C1</b>-<b>C3</b>), formed from three positively charged fluorophores (<b>A1</b>-<b>A3</b>) and one cucurbit[7]uril (CB[7]). The ability of this three-element array to simultaneously recognize 10 bacterial species within just 30 s was remarkable, boasting an impressive 100% accuracy. Additionally, the array excelled at distinguishing among various bacterial mixtures and enabled the quantitative detection of common bacterial strains. Notably, it has been skillfully applied to differentiate 10 bacterial samples in urine, achieving excellent differentiation and showcasing promising potential for medical diagnostic applications.

Analytical ChemistryVol. 96(36)
Nanjing University of Chinese Medicine (CN), China Pharmaceutical University (CN), Hubei University of Science and Technology (CN), Southern Medical University (CN)
National Natural Science Foundation of China, Ministry of Education of the People's Republic of China, Natural Science Foundation of Guangdong Province, Natural Science Foundation of Jiangsu Province
Openalex Percentile: Top 6%
Luminescence and Fluorescent Materials
2.58
DOISourceOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.