Clinical phenotyping uncovers heterogeneous associations between corticosteroid treatment and survival in critically ill COVID-19 patients

Our multinational study identified three distinct clinical COVID-19 phenotypes, each exhibiting marked differences in demographic, clinical, and immunological features, and in the response to late and short-term corticosteroid treatment.

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Publication Details

Journal
Intensive Care Medicine
Published
2024-08-26
DOI
https://doi.org/10.1007/s00134-024-07593-3
Citations
21
Primary Topic
COVID-19 Clinical Research Studies
Type
article
Field-Weighted Citation Impact
8.17

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article

Clinical phenotyping uncovers heterogeneous associations between corticosteroid treatment and survival in critically ill COVID-19 patients

Daniel Schwarzkopf, Johannes G. van der Hoeven, Daniel Thomas‐Rüddel, Aron Jansen et al.
21 citations
Intensive Care Medicine
COVID-19 Clinical Research Studies
8.17
article

Clinical phenotyping uncovers heterogeneous associations between corticosteroid treatment and survival in critically ill COVID-19 patients

Daniel Schwarzkopf, Johannes G. van der Hoeven, Daniel Thomas‐Rüddel, Aron Jansen, Eckart De Bie, Jesús F. Bermejo-Martín, Jason Kennedy, Nicolette F. de Keizer, Michael Bauer, Dirk van Lier, Niklas Bruse, Matthijs Kox, Lonneke van Vught, Emma J. Kooistra, Ana Motos, Rombout Van Amstel, Antoní Torres, Christopher W. Seymour, Ferrán Barbé, Peter Pickkers
article en
21 citations

Abstract

Our multinational study identified three distinct clinical COVID-19 phenotypes, each exhibiting marked differences in demographic, clinical, and immunological features, and in the response to late and short-term corticosteroid treatment.

Intensive Care MedicineVol. 50(11)
Radboud University Nijmegen (NL), University of Pittsburgh (US), Instituto de Salud Carlos III (ES), Amsterdam UMC Location University of Amsterdam (NL), Radboud University Medical Center (NL), Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES), Hospital Clínic de Barcelona (ES), Jena University Hospital (DE), Public Health Service of Amsterdam (NL), Amsterdam University Medical Centers (NL), Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES), Universitat de Barcelona (ES), University of Amsterdam (NL)
ZonMw, European Society of Intensive Care Medicine
Openalex Percentile: Top 2%
COVID-19 Clinical Research Studies
8.17
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