Fatty acid synthesis is indispensable for Kupffer cells to eliminate bacteria in ALD progression
Our findings indicate the crucial role of de novo lipogenesis in maintaining effective KCs phagocytosis and suggest a therapeutic target for ALD based on fatty acid synthesis in KCs.
Authors
- Ye Tao (ORCID: https://orcid.org/0000-0001-5862-9520)
- Chaojie Hu (ORCID: https://orcid.org/0000-0002-5553-4873)
- Yuanyuan Fan
- Hua Wang (ORCID: https://orcid.org/0000-0002-2605-5697)
- Qing Li (ORCID: https://orcid.org/0000-0001-6784-3182)
- Liuyu Xie
- Xiaoyong Jiang
- Huaiping Zhu
- Beng Wu
Institutions
- University of Science and Technology of China (CN)
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1097/hc9.0000000000000522
- Citations
- 3
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 1.27
Funders
- Jinan University
- Fundamental Research Funds for the Central Universities