Repetitive Head Impacts and Perivascular Space Volume in Former American Football Players
These findings suggest that impaired perivascular brain clearance, as indicated by larger PVS volume, may contribute to the association observed between RHI exposure and neurodegeneration.
Authors
- Michael J. Coleman (ORCID: https://orcid.org/0000-0001-9326-7932)
- Mary Nanna
- Sylvain Bouix (ORCID: https://orcid.org/0000-0003-1326-6054)
- Jan Durant
- Judith D. Goldberg (ORCID: https://orcid.org/0000-0003-3758-6976)
- Tessa Fagle
- Katherine M. Breedlove (ORCID: https://orcid.org/0000-0003-4408-3728)
- Christine E. Chaisson (ORCID: https://orcid.org/0000-0002-3207-9257)
- Laura J. Balcer (ORCID: https://orcid.org/0000-0002-5136-4539)
- Jeffrey J. Iliff (ORCID: https://orcid.org/0000-0002-6910-0080)
- Elaine R. Peskind (ORCID: https://orcid.org/0000-0002-3667-9129)
- Rhoda Au (ORCID: https://orcid.org/0000-0001-7742-4491)
- Alhassan Al-Kharafi
- Marci Howard
- Vivian Schultz (ORCID: https://orcid.org/0009-0006-0938-8154)
- Brynn Vessey
- Sarah Jane Banks (ORCID: https://orcid.org/0009-0001-6156-0605)
- Joseph Palmisano (ORCID: https://orcid.org/0000-0001-6000-3025)
- Neil W. Kowall (ORCID: https://orcid.org/0000-0002-6624-0213)
- Charles R. Marmar (ORCID: https://orcid.org/0000-0001-8427-5607)
- Raelynn de la Cruz
- Daniel S. Marcus (ORCID: https://orcid.org/0000-0001-5662-5358)
- Charles H. Adler (ORCID: https://orcid.org/0000-0002-1045-2743)
- Jennifer Fitzsimmons
- Debra Babcock
- Robert C. Cantu (ORCID: https://orcid.org/0009-0002-4300-4063)
- Amy Duffy
- Hillary Protas (ORCID: https://orcid.org/0000-0003-2974-8998)
- Farshid Sepehrband (ORCID: https://orcid.org/0000-0002-4483-5961)
- Michelle Montague (ORCID: https://orcid.org/0000-0003-4448-1574)
- Gustavo Mercier (ORCID: https://orcid.org/0000-0002-9695-1550)
- Inga Katharina Koerte (ORCID: https://orcid.org/0000-0003-1281-9286)
- Alexander Lin (ORCID: https://orcid.org/0000-0001-8236-880X)
- Madison Sestak
- Brian Mayville
- Kerrin Gallagher
- Yogesh Rathi (ORCID: https://orcid.org/0000-0002-9946-2314)
- Liliana Serrano (ORCID: https://orcid.org/0000-0002-3621-0697)
- Lindsay A. Farrer (ORCID: https://orcid.org/0000-0001-5533-4225)
- EO Ojo (ORCID: https://orcid.org/0000-0001-8332-8324)
- Christin Nance
- Jennifer V. Wethe (ORCID: https://orcid.org/0000-0003-2911-1129)
- Juan Piantino (ORCID: https://orcid.org/0000-0002-8861-5709)
- Leonard Jung (ORCID: https://orcid.org/0009-0004-2125-5923)
- William Runge
- Ofer Pasternak (ORCID: https://orcid.org/0000-0002-7078-6446)
- Yvonne W. Lui (ORCID: https://orcid.org/0000-0002-9984-9164)
- Jenny Gurney (ORCID: https://orcid.org/0000-0001-8988-7522)
- Charles Bernick (ORCID: https://orcid.org/0000-0003-4040-3587)
- Kathleen McLaughlin (ORCID: https://orcid.org/0000-0001-8790-566X)
- Brittany Pine
- Irene Simkin
- Megan Mariani
- Eric M. Reiman (ORCID: https://orcid.org/0000-0002-0705-3696)
- Taylor Platt
- Michael D. McClean (ORCID: https://orcid.org/0000-0002-3902-8823)
- Cara L. Kim
- Elizabeth Rizzoni
- Nicolette Harmon
- James Otis (ORCID: https://orcid.org/0000-0002-6454-4205)
- Kaitlin Hartlage (ORCID: https://orcid.org/0009-0008-6732-1286)
- David W. Dodick (ORCID: https://orcid.org/0000-0002-9486-6790)
- Yonas E. Geda (ORCID: https://orcid.org/0000-0003-1187-7230)
- Jeffrey L. Cummings (ORCID: https://orcid.org/0000-0001-8944-4158)
- Thomas Wısnıewskı (ORCID: https://orcid.org/0000-0002-3379-8966)
- Michael L. Alosco (ORCID: https://orcid.org/0000-0002-8113-8428)
- Jun Lü (ORCID: https://orcid.org/0000-0002-2678-2923)
- William Barr (ORCID: https://orcid.org/0000-0001-7711-7758)
- Nicole Gullotti
- Shannon E. Conneely (ORCID: https://orcid.org/0000-0001-9076-3973)
- Carolyn Finney
- Sammie Martin
- Fatima Tuz‐Zahra (ORCID: https://orcid.org/0000-0003-1763-255X)
- Daniel H. Daneshvar (ORCID: https://orcid.org/0000-0003-3691-9513)
- Annelise Silva
- Edward P. Riley (ORCID: https://orcid.org/0000-0001-8747-891X)
- Robert A. Stern (ORCID: https://orcid.org/0000-0002-5008-077X)
- Douglas S. Annis (ORCID: https://orcid.org/0000-0002-4897-8759)
- Elena M. Bonke (ORCID: https://orcid.org/0000-0002-8547-7283)
- Richard M. Greenwald
- Jason Miller (ORCID: https://orcid.org/0000-0002-6912-2925)
- Yi Su (ORCID: https://orcid.org/0000-0002-5834-8240)
- Thomas Osgood
- Courtney Diamond (ORCID: https://orcid.org/0000-0003-2022-6501)
- Alondra Andino
- Janani Ramachandran (ORCID: https://orcid.org/0000-0003-1231-1749)
- Robert Helm (ORCID: https://orcid.org/0000-0002-4562-6950)
- Tim L. T. Wiegand (ORCID: https://orcid.org/0009-0009-6897-0939)
- Elizabeth A. Colasurdo
- Andrew Serrano
- Kaeson Kaylegian
- Rachelle Long
- Hector Arciniega (ORCID: https://orcid.org/0000-0002-5565-9633)
- Brett Martin
- Jason Weller (ORCID: https://orcid.org/0000-0003-0387-5542)
- Yorghos Tripodis (ORCID: https://orcid.org/0000-0003-2190-7608)
- Robert Turner (ORCID: https://orcid.org/0000-0003-4229-7087)
- Eduardo Coello (ORCID: https://orcid.org/0000-0002-1240-3507)
- Aaron Ritter
- Priscilla Sandoval
- Olivia Haller
- Keith A. Johnson (ORCID: https://orcid.org/0000-0002-5916-6043)
- Kenneth Marek (ORCID: https://orcid.org/0000-0002-4197-5627)
- Jesse Mez (ORCID: https://orcid.org/0000-0003-1438-5442)
- Lara Pankatz
- Kewei Chen (ORCID: https://orcid.org/0000-0001-8497-3069)
- Allan George (ORCID: https://orcid.org/0000-0001-5949-8139)
- Marwan N. Sabbagh
- Conni Boker
- Lisene Hasanaj
- Sury Pulukuri
- Moragn Golceker
- Fiona Rica
- Haochen Liao
- Tennyson Hung
- Ivian Kirov
- Dianne B. Dixon
- Martha E. Shenton
- Bryce W. Falk
Institutions
- Boston University (US)
- University of Southern California (US)
- Alzheimer's Association (US)
- Brigham and Women's Hospital (US)
- Translational Genomics Research Institute (US)
- Cleveland Clinic (US)
- University of Nevada, Las Vegas (US)
- Harvard University (US)
- University of Arizona (US)
- Université du Québec à Montréal (CA)
- Oregon Health & Science University (US)
- University of Washington (US)
- Lou Ruvo Brain Institute (US)
- Massachusetts General Hospital (US)
- VA Puget Sound Health Care System (US)
- Mayo Clinic in Arizona (US)
- VA Northwest Network (US)
- Doernbecher Children's Hospital (US)
- Arizona State University (US)
- New York University (US)
- Ludwig-Maximilians-Universität München (DE)
- École de Technologie Supérieure (CA)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1001/jamanetworkopen.2024.28687
- Citations
- 8
- Primary Topic
- Traumatic Brain Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 3.09
Funders
- Eli Lilly and Company
- Biogen
- Sage Therapeutics
- Prothena
- Eisai
- Novo Nordisk
- H. Lundbeck A/S
- National Institute of Mental Health
- National Institute of Neurological Disorders and Stroke