APOL6 predicts immunotherapy efficacy of bladder cancer by ferroptosis
To conclude, our findings indicate APOL6 has potential as a predictive biomarker for immunotherapy treatment success estimation and reveal the STAT1/APOL6/GPX4 axis as a critical regulatory mechanism in BLCA.
Authors
- Yi Qu (ORCID: https://orcid.org/0000-0002-9993-8810)
- Yuting Xu (ORCID: https://orcid.org/0000-0001-7640-4018)
- Xuehai Wang (ORCID: https://orcid.org/0000-0002-1406-1846)
- Chu Zhou
- Xinyuan Zhao
- Zhiwei Fan (ORCID: https://orcid.org/0009-0008-2821-0989)
- Ruiyao Huang
- Weijian Shi
- Jialing Ruan
- Yiting Liu (ORCID: https://orcid.org/0009-0006-0620-3847)
- Lei Liu (ORCID: https://orcid.org/0000-0002-4604-4629)
Institutions
- Shanghai Jiao Tong University (CN)
- Nantong University (CN)
- Ruijin Hospital (CN)
- Sir Run Run Shaw Hospital (CN)
- Affiliated Hospital of Nantong University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1186/s12885-024-12820-7
- Citations
- 9
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.77
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province