Kidney transplant under paired kidney donation program: experience of a tertiary hospital in Mexico

Objective: To demonstrate the experience acquired in a tertiary hospital in Mexico since the implementation of the paired kidney donation (KPD) program.Material and methods: Observational, analytical, longitudinal and prospective study from september 2018 to september 2022.All G5 KDIGO chronic kidney patients who were HLA or ABO incompatible with their original donors in the pretransplant protocol and who were transplanted under the KPD program were included.Results: Thirty-four kidney transplants were performed under this program.At one year after the transplant, graft survival was 97%, glomerular filtration rate was 76.18 ( 21.91) ml/min/1.73m SC and the incidence of rejection was 17.6%.These results were statistically better than those presented in a historical group of kidney transplant recipients after desensitization due to positive flow-crossmatch test: graft survival 51.1%, glomerular filtration rate 51.79 ( 26.29) ml/min/1.73m SC and rejection incidence 51.1%.Conclusions: In Mexico, transplantation under KPD program is a successful modality when there is HLA/ABO incompatibility or sensitization.The greater use and socialization of this program can increase the national kidney transplant rate, reducing the waiting list.