Prognostic implications of margin status in association with systemic treatment in a cohort study of patients with resection of colorectal liver metastases
R1 is associated with worse outcomes in the patients who receive neoadjuvant treatment with no significant improvement with the addition of adjuvant therapy, likely representing an aggressive tumor biology. R1 did not impact OS in patients with upfront surgery who received postoperative chemotherapy.
Authors
- Tan To Cheung (ORCID: https://orcid.org/0000-0002-2633-5883)
- Carlos U. Corvera (ORCID: https://orcid.org/0000-0002-3092-8657)
- John Andrew Stauffer (ORCID: https://orcid.org/0000-0002-0126-0301)
- Gregory B. Russell (ORCID: https://orcid.org/0000-0003-0270-3618)
- Omeed Moaven (ORCID: https://orcid.org/0000-0002-0560-0457)
- Charles Cha
- Andrew D. Wisneski (ORCID: https://orcid.org/0000-0001-6455-2216)
- Cristian D. Valenzuela (ORCID: https://orcid.org/0000-0002-8694-9174)
- Perry Shen (ORCID: https://orcid.org/0000-0002-7416-7829)
- Bigyan B. Mainali
Institutions
- Atrium Health Wake Forest Baptist (US)
- University of California, San Francisco (US)
- Yale University (US)
- Louisiana Cancer Research Center (US)
- Mayo Clinic in Florida (US)
- Louisiana State University Health Sciences Center New Orleans (US)
- University of Hong Kong (HK)
Publication Details
- Journal
- Journal of Surgical Oncology
- Published
- 2024-08-25
- DOI
- https://doi.org/10.1002/jso.27846
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00