Metagenomic versus targeted next-generation sequencing for detection of microorganisms in bronchoalveolar lavage fluid among renal transplantation recipients
Although tNGS was inferior to mNGS owing to lower sensitivity and true positive rate in identifying respiratory pathogens among KTRs, both considerably outperformed CMT.
Authors
- Huan Xu (ORCID: https://orcid.org/0000-0001-5861-0707)
- Zhaoru Huang
- Fengxiang Huang (ORCID: https://orcid.org/0009-0005-2410-0051)
- Jinfeng Li (ORCID: https://orcid.org/0000-0002-4312-5917)
- Wenjun Shang (ORCID: https://orcid.org/0000-0002-9234-979X)
- Bingxue Hu (ORCID: https://orcid.org/0000-0001-9116-6249)
- Min Feng
- Lei Liu (ORCID: https://orcid.org/0009-0006-7039-0560)
- Zhigang Wang
Institutions
- Vision Medicals (China) (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-08-26
- DOI
- https://doi.org/10.3389/fimmu.2024.1443057
- Citations
- 16
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 8.13