Elevated ALT/AST ratio as a marker for NAFLD risk and severity: insights from a cross-sectional analysis in the United States
A higher ALT/AST ratio was independently associated with a significantly higher risk of NAFLD and liver fibrosis within American cohorts. This link is robust among females, children, and adolescents. ALT/AST ratio can be used as a simple and effective noninvasive biomarker to identify individuals with high risk of NAFLD.
Authors
- Yanyan Xuan (ORCID: https://orcid.org/0000-0002-4670-1895)
- Zhiqiang Yu
- Qin Zhang (ORCID: https://orcid.org/0000-0002-6121-6513)
- Dingting Wu
- Dongdong Zhou (ORCID: https://orcid.org/0009-0000-9793-2581)
- Jingbo Yu (ORCID: https://orcid.org/0000-0002-3644-3132)
Institutions
- Ningbo University (CN)
- Sir Run Run Shaw Hospital (CN)
- Zhejiang Business Technology Institute (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-08-26
- DOI
- https://doi.org/10.3389/fendo.2024.1457598
- Citations
- 56
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 21.65