Clinical utility of repeated rebiopsy for EGFR T790M mutation detection in non-small cell lung cancer

In this study, among patients who initially tested negative for T790M in rebiopsy, repeated rebiopsies uncovered an additional 23.5% T790M positivity. Particularly, it is suggested that repeated rebiopsies may be valuable for patients with prolonged EGFR TKI usage, better responses to treatment, and bone metastasis.

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Publication Details

Journal
Frontiers in Oncology
Published
2024-08-26
DOI
https://doi.org/10.3389/fonc.2024.1452947
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00

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article

Clinical utility of repeated rebiopsy for EGFR T790M mutation detection in non-small cell lung cancer

Chi Young Kim, Se Hyun Kwak, Yoon Soo Chang, Seok‐Jae Heo et al.
Frontiers in Oncology
Lung Cancer Treatments and Mutations
article

Clinical utility of repeated rebiopsy for EGFR T790M mutation detection in non-small cell lung cancer

Chi Young Kim, Se Hyun Kwak, Yoon Soo Chang, Seok‐Jae Heo, Kyeong Yeon Kim, Sang Hoon Lee, Eun Young Kim, Eun Hye Lee
article en

Abstract

In this study, among patients who initially tested negative for T790M in rebiopsy, repeated rebiopsies uncovered an additional 23.5% T790M positivity. Particularly, it is suggested that repeated rebiopsies may be valuable for patients with prolonged EGFR TKI usage, better responses to treatment, and bone metastasis.

Frontiers in OncologyVol. 14
Yonsei University (KR), Severance Hospital (KR), Gangnam Severance Hospital (KR)
National Research Foundation, National Research Foundation of Korea, Ministry of Science and ICT, South Korea
Good health and well-being
Openalex Percentile: Top 75%
Lung Cancer Treatments and Mutations
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Clinical utility of repeated rebiopsy for EGFR T790M mutation detection in non-small cell lung cancer — Chi Young Kim, Se Hyun Kwak, et al. · Frontiers in Oncology (2024) | TGRS Research Map | TGRS