BRAF-induced <i>EHF</i> Expression Affects <i>TERT</i> in Aggressive Papillary Thyroid Cancer
The ETS transcription factor EHF is associated with poor prognosis in PTC. This is potentially mediated by BRAF-induced upregulation of EHF, which in turn increases TERT expression in TERT promoter mutated cells.
Authors
- Ninni Mu (ORCID: https://orcid.org/0000-0002-3887-880X)
- Jan Zedenius (ORCID: https://orcid.org/0000-0003-2833-3758)
- Dawei Xu (ORCID: https://orcid.org/0000-0003-3141-4524)
- Catharina Larsson (ORCID: https://orcid.org/0000-0003-4813-3657)
- C. Christofer Juhlin (ORCID: https://orcid.org/0000-0002-5945-9081)
- Weng‐Onn Lui (ORCID: https://orcid.org/0000-0003-4717-4473)
- Inga‐Lena Nilsson (ORCID: https://orcid.org/0000-0002-8966-3729)
- Yiyi Xu (ORCID: https://orcid.org/0009-0009-0460-1288)
- Na Wang (ORCID: https://orcid.org/0000-0003-0806-4247)
- Jiwei Gao (ORCID: https://orcid.org/0000-0002-9786-853X)
Institutions
- Karolinska University Hospital (SE)
- Karolinska Institutet (SE)
- Zhejiang Cancer Hospital (CN)
- Cancer Hospital of Chinese Academy of Medical Sciences (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1210/clinem/dgae589
- Citations
- 5
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.79
Funders
- Cancerfonden
- Karolinska Institutet
- Stockholms Läns Landsting
- Vetenskapsrådet
- China Scholarship Council