Predicting early appropriate therapy for patients infected by carbapenem-resistant Gram-negative pathogens in intensive care units in Italy
Based on confirmed susceptibility rates and reported ICU prevalence of multiple Gram-negative species, cefiderocol showed a higher predicted therapeutic coverage and utility in ICUs compared with comparator beta-lactam-beta-lactamase inhibitor antibiotics. Cefiderocol may be a promising early treatment option for patients at high risk of carbapenem-resistant Gram-negative bacterial infections in the ICU.
Authors
- Christopher Longshaw (ORCID: https://orcid.org/0000-0002-5586-7256)
- Gianpaola Monti
- Matteo Bassetti (ORCID: https://orcid.org/0000-0002-0145-9740)
- Anne Santerre Henriksen (ORCID: https://orcid.org/0000-0002-7294-6386)
Institutions
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- Shionogi (United States) (US)
- Ospedale Policlinico San Martino (IT)
Publication Details
- Journal
- Antimicrobial Resistance and Infection Control
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1186/s13756-024-01452-y
- Citations
- 3
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.51
Funders
- Shionogi