Generation of human hepatobiliary organoids with a functional bile duct from chemically induced liver progenitor cells
This study demonstrated the potential of human HBOs as an efficient model for studying hepatobiliary diseases, drug discovery, and personalized medicine.
Authors
- Yuta Kawaguchi
- Mampei Yamashita (ORCID: https://orcid.org/0000-0003-4660-2448)
- Susumu Eguchi (ORCID: https://orcid.org/0000-0002-7876-0152)
- Akihiko Soyama (ORCID: https://orcid.org/0000-0003-2932-4300)
- Weili Gu (ORCID: https://orcid.org/0000-0002-0448-110X)
- Kengo Kanetaka (ORCID: https://orcid.org/0000-0002-1620-7044)
- Masaaki Hidaka (ORCID: https://orcid.org/0000-0001-8191-6405)
- Peilin Li (ORCID: https://orcid.org/0000-0002-9136-0882)
- Hanako Tetsuo
- Daisuke Miyamoto (ORCID: https://orcid.org/0000-0003-0367-9904)
- Hajime Imamura (ORCID: https://orcid.org/0000-0002-7205-7757)
- Hajime Matsushima (ORCID: https://orcid.org/0000-0002-1577-6587)
- Masayuki Fukumoto (ORCID: https://orcid.org/0000-0002-0792-0964)
- Tomohiko Adachi (ORCID: https://orcid.org/0000-0001-7025-6173)
- Takanobu Hara
Institutions
- Guangzhou First People's Hospital (CN)
- Nagasaki University (JP)
- South China University of Technology (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-08-26
- DOI
- https://doi.org/10.1186/s13287-024-03877-z
- Citations
- 6
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 2.22
Funders
- Japan Society for the Promotion of Science