MvGraphDTA: multi-view-based graph deep model for drug-target affinity prediction by introducing the graphs and line graphs

During the experiments, we performed data augmentation on all the training sets used. Experimental results showed that MvGraphDTA outperformed the competitive state-of-the-art methods on benchmark datasets for DTA prediction. Additionally, we evaluated the universality and generalization performance of MvGraphDTA on additional datasets. Experimental outcomes revealed that MvGraphDTA exhibited good universality and generalization capability, making it a reliable tool for drug-target interaction prediction.

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Publication Details

Journal
BMC Biology
Published
2024-08-26
DOI
https://doi.org/10.1186/s12915-024-01981-3
Citations
12
Primary Topic
Computational Drug Discovery Methods
Type
article
Field-Weighted Citation Impact
4.34

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article

MvGraphDTA: multi-view-based graph deep model for drug-target affinity prediction by introducing the graphs and line graphs

Meng‐Liang Wen, Kai-Yang Zhong, Yi Li, Shujuan Li et al.
12 citations
BMC Biology
Computational Drug Discovery Methods
4.34
article

MvGraphDTA: multi-view-based graph deep model for drug-target affinity prediction by introducing the graphs and line graphs

Meng‐Liang Wen, Kai-Yang Zhong, Yi Li, Shujuan Li, Shuang‐Qing Lv, Xin Zeng, Pei-Yan Meng
article en
12 citations

Abstract

During the experiments, we performed data augmentation on all the training sets used. Experimental results showed that MvGraphDTA outperformed the competitive state-of-the-art methods on benchmark datasets for DTA prediction. Additionally, we evaluated the universality and generalization performance of MvGraphDTA on additional datasets. Experimental outcomes revealed that MvGraphDTA exhibited good universality and generalization capability, making it a reliable tool for drug-target interaction prediction.

BMC BiologyVol. 22(1)
Yunnan University (CN), Yunnan Institute of Endemic Diseases Control and Prevention (CN), Dali University (CN)
Yunnan University
Openalex Percentile: Top 5%
Computational Drug Discovery Methods
4.34
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MvGraphDTA: multi-view-based graph deep model for drug-target affinity prediction by introducing the graphs and line graphs — Meng‐Liang Wen, Kai-Yang Zhong, et al. · BMC Biology (2024) | TGRS Research Map | TGRS