Brief Report: Impact of Maintenance Pemetrexed Cessation on Clinical Outcomes of Patients With Metastatic Nonsquamous NSCLC

In this study of patients with metastatic nonsquamous NSCLC who received maintenance pemetrexed and pembrolizumab, patients who stopped pemetrexed due to toxicity experienced similar outcomes to those who continued with pemetrexed. The optimal duration of maintenance chemotherapy should be further evaluated in the immunotherapy era.

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Publication Details

Journal
JTO Clinical and Research Reports
Published
2024-08-25
DOI
https://doi.org/10.1016/j.jtocrr.2024.100717
Citations
1
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.42
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article

Brief Report: Impact of Maintenance Pemetrexed Cessation on Clinical Outcomes of Patients With Metastatic Nonsquamous NSCLC

Wade T. Iams, Spencer Lessans, Heidi Chen, M Lu et al.
1 citations
JTO Clinical and Research Reports
Lung Cancer Treatments and Mutations
0.42
article

Brief Report: Impact of Maintenance Pemetrexed Cessation on Clinical Outcomes of Patients With Metastatic Nonsquamous NSCLC

Wade T. Iams, Spencer Lessans, Heidi Chen, M Lu, Michael Libre, Shreya Bhatia
article en
1 citations

Abstract

In this study of patients with metastatic nonsquamous NSCLC who received maintenance pemetrexed and pembrolizumab, patients who stopped pemetrexed due to toxicity experienced similar outcomes to those who continued with pemetrexed. The optimal duration of maintenance chemotherapy should be further evaluated in the immunotherapy era.

JTO Clinical and Research ReportsVol. 5(11)
Vanderbilt University (US), Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center (US)
Zero hunger
Openalex Percentile: Top 34%
Lung Cancer Treatments and Mutations
0.42
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