Differences and potential mechanisms of theta oscillation and temporoparietal and temporal-central networks in temporal lobe epilepsy patients with unilateral hippocampal sclerosis
Theta power is an important EEG indicator of mTLE-HS, positively correlates with epilepsy severity and seizure frequency, and has network properties that can be observed outside the lesion. Moreover, the usage of third-generation ASMs did not affect the risk of increased theta power. Lastly, the temporoparietal and temporal-central networks are likely to be causative pathways in epilepsy patients with cognitive impairment. This study provides a potential guideline for the treatment of mTLE-HS in clinical practice.
Authors
- Jing Lu (ORCID: https://orcid.org/0000-0002-3519-3055)
- Yingying Tang (ORCID: https://orcid.org/0000-0001-5813-0308)
- Enzhi Li
- Xiaoting Hao (ORCID: https://orcid.org/0000-0002-0372-1634)
- Chenxi Qiu (ORCID: https://orcid.org/0000-0002-0314-5307)
- Dong Chi Zhou (ORCID: https://orcid.org/0000-0001-7101-4125)
- Li‐Ju Wang (ORCID: https://orcid.org/0000-0003-2745-2819)
- Zhiyi Liu (ORCID: https://orcid.org/0000-0002-8122-8474)
- Sijia Guo (ORCID: https://orcid.org/0000-0002-8869-8743)
- Bo Yan (ORCID: https://orcid.org/0000-0001-5767-2535)
- Yingqi Jiang
- Chenxi Zhong
- Ying Liu (ORCID: https://orcid.org/0000-0002-7164-962X)
Institutions
- University of Electronic Science and Technology of China (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Chengdu University (CN)
- Sichuan Provincial Hospital of Traditional Chinese Medicine (CN)
- Sichuan University of Science and Engineering (CN)
Publication Details
- Journal
- Acta Epileptologica
- Published
- 2024-08-25
- DOI
- https://doi.org/10.1186/s42494-024-00170-7
- Citations
- 1
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.39