Affective disorders accompanied by cognitive impairment in patients with a cardiological profile: prevalence, multimorbidity, medical and social risk factors

Clinical and medico-social issues of affective pathology combined with cognitive impairment in cardiac patients are a serious problem of modern medicine. This multimorbidity is characterized by higher risks of social maladjustment, disability, concomitant health problems and mortality. Cognitive dysfunctions in affective pathology are of great clinical and social importance, but their initial manifestations in cardiac patients are still insufficiently diagnosed. This leads to missed opportunities for the prevention of cognitive deficits. This review presents epidemiological data, pathological mechanisms, biological and psychosocial problems of multimorbid connections of cardiovascular, affective and cognitive pathology. Full-text articles, fragments of monographs selected by keywords in the databases Scopus, Web of Science, Medline, RSCI, eLibrary.ru, disserCat.ru, Psychiatrist, Sciencedirect were used.