Anti-GBM Nephritis in an 11-Year-Old Female Child: A Rare Case Report

Anti-glomerular basement membrane (GBM) nephritis is a rare autoimmune condition involving the glomerular basement membrane of the kidneys. This case report describes an 11-year-old female who presented with edema, decreased urine output, and altered sensorium, progressing to hypertension and requiring emergent hemodialysis. A renal biopsy showing Immunoglobulin G (IgG) linear deposits confirmed the diagnosis. The patient was treated with intravenous methylprednisolone and antihypertensives and then scheduled for regular dialysis. This case underscores the critical need for early diagnosis and aggressive management to prevent severe complications in pediatric anti-GBM disease.

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Journal
Cureus
Published
2024-08-25
DOI
https://doi.org/10.7759/cureus.67736
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
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article

Anti-GBM Nephritis in an 11-Year-Old Female Child: A Rare Case Report

Manojkumar G Patil, Shailaja Mane, Manoj Matnani, Neha Thorbole et al.
Cureus
Renal Diseases and Glomerulopathies
article

Anti-GBM Nephritis in an 11-Year-Old Female Child: A Rare Case Report

Manojkumar G Patil, Shailaja Mane, Manoj Matnani, Neha Thorbole, Shivani Kale
article en

Abstract

Anti-glomerular basement membrane (GBM) nephritis is a rare autoimmune condition involving the glomerular basement membrane of the kidneys. This case report describes an 11-year-old female who presented with edema, decreased urine output, and altered sensorium, progressing to hypertension and requiring emergent hemodialysis. A renal biopsy showing Immunoglobulin G (IgG) linear deposits confirmed the diagnosis. The patient was treated with intravenous methylprednisolone and antihypertensives and then scheduled for regular dialysis. This case underscores the critical need for early diagnosis and aggressive management to prevent severe complications in pediatric anti-GBM disease.

CureusVol. 16(8)
Dr. D. Y. Patil Medical College, Hospital and Research Centre (IN), Dr. D.Y. Patil Vidyapeeth, Pune (IN)
Gender equality
Openalex Percentile: Top 82%
Renal Diseases and Glomerulopathies
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Anti-GBM Nephritis in an 11-Year-Old Female Child: A Rare Case Report — Manojkumar G Patil, Shailaja Mane, et al. · Cureus (2024) | TGRS Research Map | TGRS