Gut microbiota mediates anxiety-like behaviors induced by chronic infection of <i>Toxoplasma gondii</i> in mice
The present study uncovers a novel role of gut microbiota in mediating the anxiety-like behaviors induced by chronic <i>T. gondii</i> infection. Moreover, we show that DBM supplementation has a beneficial effect on anxiety. Overall, these findings provide new insights into the treatment of <i>T. gondii</i>-related mental disorders.
Authors
- Daxiang Xu
- Yinghua Yu (ORCID: https://orcid.org/0000-0003-2508-7512)
- Jianping Cao (ORCID: https://orcid.org/0000-0002-1974-0047)
- Shimin Tan
- Yuying Zhou
- Xiaotong Luo
- Yingting Huang
- Kuiyang Zheng (ORCID: https://orcid.org/0000-0002-1896-7485)
- Yunqiu Liu (ORCID: https://orcid.org/0000-0002-7401-0899)
- Wei Xing Pan (ORCID: https://orcid.org/0000-0003-2641-1759)
- Cheng He (ORCID: https://orcid.org/0000-0002-8102-8245)
- Yongsheng Zhang
- Renxian Tang (ORCID: https://orcid.org/0000-0001-7235-0729)
- Xiaoying Yang (ORCID: https://orcid.org/0000-0003-1776-2469)
- Fenfen Sun
- Xiaokang Tian
- Kun Yin (ORCID: https://orcid.org/0000-0003-0493-3281)
- Xiangyang Li (ORCID: https://orcid.org/0000-0001-9679-6549)
Institutions
- National Institute for Parasitic Diseases (CN)
- Xuzhou Medical College (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Gut Microbes
- Published
- 2024-08-25
- DOI
- https://doi.org/10.1080/19490976.2024.2391535
- Citations
- 25
- Primary Topic
- Toxoplasma gondii Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 12.89
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province
- Natural Science Foundation of Shandong Province
- Xuzhou Medical University
- National Health Commission of the People's Republic of China
- Government of Shandong Province