Fluoroquinolones in orthopaedic infection: balancing risks and rewards
This article discusses the recent regulatory restrictions on the use of fluoroquinolones and their impact on treating orthopaedic infections. We focus on the balance between the benefits and risks of fluoroquinolones in scenarios involving severe infections where alternative antibiotics may be less effective. The discussion includes a summary of recent evidence on adverse effects and the implications for clinical practice.
Authors
- Antonia Scobie (ORCID: https://orcid.org/0000-0002-0941-9866)
- Louise Dunsmure (ORCID: https://orcid.org/0000-0002-8502-5092)
- Simon Warren (ORCID: https://orcid.org/0000-0001-6857-6303)
- Matthew Scarborough (ORCID: https://orcid.org/0000-0002-0455-0785)
- Tariq Azamgarhi (ORCID: https://orcid.org/0000-0001-7024-9379)
- Viola Peter-Akhigbe
Institutions
- Royal National Orthopaedic Hospital (GB)
- Royal National Orthopaedic Hospital NHS Trust (GB)
- Oxford University Hospitals NHS Trust (GB)
- University College London (GB)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1093/jac/dkae286
- Citations
- 2
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.15