A dynamic variant of Takotsubo cardiomyopathy mimicking apical hypertrophic cardiomyopathy: a case report

Following emotional stress, takotsubo cardiomyopathy is understood caused by various mechanisms: catecholamine surge, inflammation, or transient ischaemia event leading to dysregulated cellular mechanisms. This results in myocardial oedema and increased wall stiffness leading to non-type 1 coronary plaque event-related regional wall motion abnormalities.In this instance, the initial two cMRI studies reported morphological features consistent with apical HCM, however, a subsequent examination demonstrated resolution of these features. The key to delineating these distinct pathologies lies in myocardial T1 times that exceeded what is normally observed in HCM, the absence of late gadolinium enhancement and ECV values which favour takotsubo cardiomyopathy.

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Publication Details

Journal
European Heart Journal - Case Reports
Published
2024-08-23
DOI
https://doi.org/10.1093/ehjcr/ytae432
Citations
2
Primary Topic
Takotsubo Cardiomyopathy and Associated Phenomena
Type
article
Field-Weighted Citation Impact
0.80
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article

A dynamic variant of Takotsubo cardiomyopathy mimicking apical hypertrophic cardiomyopathy: a case report

Andrew Flett, David Gant, Robert Adam, Chitsa Seyani et al.
2 citations
European Heart Journal - Case Reports
Takotsubo Cardiomyopathy and Associated Phenomena
0.80
article

A dynamic variant of Takotsubo cardiomyopathy mimicking apical hypertrophic cardiomyopathy: a case report

Andrew Flett, David Gant, Robert Adam, Chitsa Seyani, James Shambrook
article en
2 citations

Abstract

Following emotional stress, takotsubo cardiomyopathy is understood caused by various mechanisms: catecholamine surge, inflammation, or transient ischaemia event leading to dysregulated cellular mechanisms. This results in myocardial oedema and increased wall stiffness leading to non-type 1 coronary plaque event-related regional wall motion abnormalities.In this instance, the initial two cMRI studies reported morphological features consistent with apical HCM, however, a subsequent examination demonstrated resolution of these features. The key to delineating these distinct pathologies lies in myocardial T1 times that exceeded what is normally observed in HCM, the absence of late gadolinium enhancement and ECV values which favour takotsubo cardiomyopathy.

European Heart Journal - Case ReportsVol. 9(1)
University Hospital Southampton NHS Foundation Trust (GB)
Good health and well-being
Openalex Percentile: Top 24%
Takotsubo Cardiomyopathy and Associated Phenomena
0.80
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A dynamic variant of Takotsubo cardiomyopathy mimicking apical hypertrophic cardiomyopathy: a case report — Andrew Flett, David Gant, et al. · European Heart Journal - Case Reports (2024) | TGRS Research Map | TGRS