Leukocyte Telomere Length and Mitochondrial DNA Copy Number in Treatment-Resistant Depression and Response to Electroconvulsive Therapy

Ours is the first longitudinal study exploring the role of LTL and mtDNA-cn in response to ECT. Findings of this pilot investigation suggest that LTL and mtDNA-cn may constitute disease biomarkers for TRD but are not involved in response to ECT.

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Publication Details

Journal
Journal of Ect
Published
2024-08-21
DOI
https://doi.org/10.1097/yct.0000000000001060
Primary Topic
Tryptophan and brain disorders
Type
article
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0.00
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article

Leukocyte Telomere Length and Mitochondrial DNA Copy Number in Treatment-Resistant Depression and Response to Electroconvulsive Therapy

Massimo Gennarelli, Marco Bortolomasi, Donatella Congiu, Alessio Squassina et al.
Journal of Ect
Tryptophan and brain disorders
article

Leukocyte Telomere Length and Mitochondrial DNA Copy Number in Treatment-Resistant Depression and Response to Electroconvulsive Therapy

Massimo Gennarelli, Marco Bortolomasi, Donatella Congiu, Alessio Squassina, Mirko Manchia, Pasquale Paribello, Claudia Pisanu, Valentina Menesello, Alessandra Minelli, Anna Meloni, Bernhard T. Baune, Maria Abate
article en

Abstract

Ours is the first longitudinal study exploring the role of LTL and mtDNA-cn in response to ECT. Findings of this pilot investigation suggest that LTL and mtDNA-cn may constitute disease biomarkers for TRD but are not involved in response to ECT.

Journal of EctVol. 41(2)
The University of Melbourne (AU), University of Cagliari (IT), University of Münster (DE), Florey Institute of Neuroscience and Mental Health (AU), Ospedale Santa Chiara (IT), Centro San Giovanni di Dio Fatebenefratelli (IT), University of Brescia (IT)
Good health and well-being
Openalex Percentile: Top 88%
Tryptophan and brain disorders
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Leukocyte Telomere Length and Mitochondrial DNA Copy Number in Treatment-Resistant Depression and Response to Electroconvulsive Therapy — Massimo Gennarelli, Marco Bortolomasi, et al. · Journal of Ect (2024) | TGRS Research Map | TGRS