Disrupted Balance of Short- and Long-Range Functional Connectivity Density in Patients with Herpes Zoster or Postherpetic Neuralgia: A Resting-State fMRI Study
Herpes zoster pain widely affects intra- and inter-regional functional connectivity, leading to disrupted short-range FCD and increased long-range FCD during different stages of the disease. Long-term chronic pain in PHN patients may impair the pain emotion regulation pathway. These findings could improve our understanding of the pathophysiological mechanisms of HZ and PHN and offer neuroimaging markers for HZ and PHN.
Authors
- Huiting Lv
- Jiaxin Xiong (ORCID: https://orcid.org/0009-0009-1652-0338)
- Xiaofeng Jiang
- Shunda Hong
- Jian Jiang (ORCID: https://orcid.org/0000-0001-9395-3748)
- Xian Liu (ORCID: https://orcid.org/0000-0001-7485-4517)
- Hongmei Kuang
- Lili Gu (ORCID: https://orcid.org/0000-0003-4727-4036)
- Xiaoyan Hou
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Journal of Pain Research
- Published
- 2024-08-01
- DOI
- https://doi.org/10.2147/jpr.s472349
- Citations
- 3
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangxi Province