Aspirin hypersensitivity diagnostic index (<scp>AHDI</scp>): In vitro test for diagnosing of N‐<scp>ERD</scp> based on urinary 15‐oxo‐<scp>ETE</scp> and <scp>LTE<sub>4</sub></scp> excretion
We confirmed 15-oxo-ETE as a second to cysteinyl leukotrienes biomarker of N-ERD. An index based on these eicosanoids corrected for sex and Lund-Mackay score has a similar diagnostic value as gold standard oral aspirin challenge in the studied group of patients with asthma.
Authors
- Joanna Szaleniec (ORCID: https://orcid.org/0000-0001-7980-0497)
- Hanna Plutecka (ORCID: https://orcid.org/0000-0002-9551-8149)
- Adam Ćmiel (ORCID: https://orcid.org/0000-0002-7015-1707)
- Bogdan Jakieła (ORCID: https://orcid.org/0000-0003-0444-981X)
- Marek Sanak (ORCID: https://orcid.org/0000-0001-7635-8103)
- Lucyna Mastalerz (ORCID: https://orcid.org/0000-0002-8994-0036)
- Gabriela Trąd
- Anna Gielicz (ORCID: https://orcid.org/0000-0002-2128-2145)
- Agnieszka Gawlewicz‐Mroczka
- Radosłąw Kacorzyk (ORCID: https://orcid.org/0000-0002-2778-2407)
- Piotr Szatkowski (ORCID: https://orcid.org/0000-0003-4621-9262)
Institutions
- Jagiellonian University (PL)
- AGH University of Krakow (PL)
Publication Details
- Journal
- Allergy
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1111/all.16281
- Citations
- 15
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 6.72
Funders
- Narodowe Centrum Nauki