Tumour masquerading juvenile angiofibroma in a female; unveiling glomangiopericytoma-a rare sinonasal histopathology

Sinonasal tumours of varying histology are not unusual in otolaryngology surgical practice. Juvenile angiofibroma (JAs) are vascular tumours usually occurring in adolescent male population; but rare in females. But similar clinical and radiological presentations are possible in females inducing strong suspicion of JA which needs to be ruled out by detailed evaluation. Here we present a case of a young female in her 20s who presented with a bleeding nasal mass which was finally diagnosed as sinonasal glomangiopericytoma which is a very rare sinonasal tumour. Tumours resembling JA do present in the female population but rarely turn out to be JA. A strong index of suspicion along with a handful of special blood investigations to rule out androgen insensitivity syndrome is mandatory.

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Publication Details

Journal
BMJ Case Reports
Published
2024-08-01
DOI
https://doi.org/10.1136/bcr-2023-256667
Primary Topic
Head and Neck Surgical Oncology
Type
article
Field-Weighted Citation Impact
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article

Tumour masquerading juvenile angiofibroma in a female; unveiling glomangiopericytoma-a rare sinonasal histopathology

Jijitha Lakshmanan, Arun Alexander, Karthikeyan Ramasamy, Sivaraman Ganesan
BMJ Case Reports
Head and Neck Surgical Oncology
article

Tumour masquerading juvenile angiofibroma in a female; unveiling glomangiopericytoma-a rare sinonasal histopathology

Jijitha Lakshmanan, Arun Alexander, Karthikeyan Ramasamy, Sivaraman Ganesan
article en

Abstract

Sinonasal tumours of varying histology are not unusual in otolaryngology surgical practice. Juvenile angiofibroma (JAs) are vascular tumours usually occurring in adolescent male population; but rare in females. But similar clinical and radiological presentations are possible in females inducing strong suspicion of JA which needs to be ruled out by detailed evaluation. Here we present a case of a young female in her 20s who presented with a bleeding nasal mass which was finally diagnosed as sinonasal glomangiopericytoma which is a very rare sinonasal tumour. Tumours resembling JA do present in the female population but rarely turn out to be JA. A strong index of suspicion along with a handful of special blood investigations to rule out androgen insensitivity syndrome is mandatory.

BMJ Case ReportsVol. 17(8)
Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
Good health and well-being, Gender equality
Openalex Percentile: Top 74%
Head and Neck Surgical Oncology
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