Protein characterization of an Indonesian isolate of foot and mouth disease virus inactivated with formaldehyde and binary ethylenimine
This study found that 0.04% formaldehyde, alone or in combination with 0.001 M BEI, was effective for inactivating and preserving the specific molecular weight of Serotype O FMDV protein. The limitation of this study was the inactivations of the virus have not yet been tested for their potency on experimental animals. Further research is warranted to investigate the inactivation kinetics of these materials, including their potency on experimental animals. Additionally, a comparison of the inactivation rates between 0.04% formaldehyde alone and the combination with BEI would help to determine the optimal inactivation agent for future applications.
Authors
- Firdausy Kurnia Maulana (ORCID: https://orcid.org/0000-0002-8276-6151)
- Yulianna Puspitasari (ORCID: https://orcid.org/0000-0002-1198-8515)
- Yudha Kurniawan (ORCID: https://orcid.org/0009-0003-9462-3662)
- Diyantoro Diyantoro
- Wiwiek Tyasningsih (ORCID: https://orcid.org/0000-0003-0604-8534)
- Fedik Abdul Rantam (ORCID: https://orcid.org/0000-0001-8182-1465)
- Helen Susilowati (ORCID: https://orcid.org/0000-0002-3358-5231)
- Kusnoto Kusnoto (ORCID: https://orcid.org/0000-0003-3915-654X)
- Jola Rahmahani (ORCID: https://orcid.org/0000-0001-9103-3200)
- Suryo Kuncorojakti (ORCID: https://orcid.org/0000-0001-5170-9982)
- Ahmad Aswin (ORCID: https://orcid.org/0009-0009-9767-8187)
- Talenta Miracle Tobing
- Fadia Azzahra
Institutions
- Universitas Airlangga (ID)
Publication Details
- Journal
- Veterinary World
- Published
- 2024-08-01
- DOI
- https://doi.org/10.14202/vetworld.2024.1836-1845
- Citations
- 1
- Primary Topic
- Animal Disease Management and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- Kementerian Pendidikan, Kebudayaan, Riset, dan Teknologi