miRNAs as potential biomarkers for subclinical atherosclerosis in Sjögren’s disease
In conclusion, patients with SjD demonstrated differences in their expression of miRNAs linked to regulation of endothelial function. Reduction of specific miRNAs was associated with increased cardiovascular risk, suggesting a potentially protective role for these miRNAs. Furthermore, miR-92a-3p could be helpful for molecular detection of early-stage atherosclerosis and increased cardiovascular risk in SjD.
Authors
- Thomas Skripuletz (ORCID: https://orcid.org/0000-0001-8550-335X)
- Tabea Seeliger (ORCID: https://orcid.org/0000-0002-6018-6826)
- Nadine Zehrfeld (ORCID: https://orcid.org/0000-0003-1556-790X)
- Fiona Engelke (ORCID: https://orcid.org/0000-0002-5673-1705)
- Thomas Thum (ORCID: https://orcid.org/0000-0003-4360-1511)
- Torsten Witte (ORCID: https://orcid.org/0000-0003-4531-0267)
- Anselm A. Derda (ORCID: https://orcid.org/0000-0003-1968-189X)
- Kristina Sonnenschein
- Malin Abelmann
- Christian Baer
- Diana Ernst (ORCID: https://orcid.org/0000-0003-0736-6243)
- Sabrina Benz
Institutions
- Medizinische Hochschule Hannover (DE)
Publication Details
- Journal
- RMD Open
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1136/rmdopen-2024-004434
- Citations
- 8
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 2.61
Funders
- Novartis Pharma