Identification of pivotal genes and crucial pathways in liver fibrosis through WGCNA analysis
This study identified four key genes (Cftr, Cldn4, Map2, Spp1) that are significantly associated with liver fibrosis. These genes are upregulated in liver fibrosis and could potentially as biomarkers for diagnosis and targets for therapeutic interventions.
Authors
- Qiuming Su
- Xibing Zhang
- Jianghua Ran
- Kepu Zheng (ORCID: https://orcid.org/0009-0007-6426-9956)
- Fuli Yang
- Ruichao Wu
- Wang Li (ORCID: https://orcid.org/0000-0002-7618-7524)
- Fang Liu (ORCID: https://orcid.org/0000-0002-9004-1599)
- Duo Wang (ORCID: https://orcid.org/0009-0000-5802-9226)
- Lei Han
- Yang Gao (ORCID: https://orcid.org/0000-0002-7910-3787)
Institutions
- Changzhi Medical College (CN)
- Kunming Medical University (CN)
Publication Details
- Journal
- Technology and Health Care
- Published
- 2024-08-20
- DOI
- https://doi.org/10.3233/thc-241142
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.77