Clinical and Ultrasonographic Remission in Bio-naïve and Bio-failure Patients with Rheumatoid Arthritis at 24 Weeks of Upadacitinib Treatment: The UPARAREMUS Real-Life Study
UPARAREMUS is the first study evaluating the efficacy of upadacitinib in reaching both clinical and US remission in patients with RA. At 24 weeks, 63.6% of patients reached the primary endpoint, the only baseline associated parameter was being bio-naïve.
Authors
- Simonetta Salemi (ORCID: https://orcid.org/0000-0003-4754-8092)
- Caterina Baldi (ORCID: https://orcid.org/0000-0002-3070-5568)
- Bruno Frediani (ORCID: https://orcid.org/0000-0002-9375-5984)
- Roberta Rosa (ORCID: https://orcid.org/0000-0002-6062-8559)
- Maria Sofia Cattaruzza (ORCID: https://orcid.org/0000-0002-7489-3564)
- Andrea Picchianti Diamanti (ORCID: https://orcid.org/0000-0002-8552-4641)
- Gian Domenico Sebastiani (ORCID: https://orcid.org/0000-0003-2969-6649)
- Maria Sole Chimenti (ORCID: https://orcid.org/0000-0002-1343-1729)
- Marco Canzoni (ORCID: https://orcid.org/0000-0001-5797-4154)
- Chiara De Lorenzo (ORCID: https://orcid.org/0000-0002-3609-4913)
- Ivan Giovannini (ORCID: https://orcid.org/0000-0002-1110-2518)
- Valentino Paci (ORCID: https://orcid.org/0000-0002-9466-8460)
- Chiara Scirocco (ORCID: https://orcid.org/0000-0002-0095-300X)
- Annamaria Iagnocco (ORCID: https://orcid.org/0000-0001-5592-724X)
- Alen Zabotti
- Michele Maria Luchetti (ORCID: https://orcid.org/0000-0001-9132-7401)
- Bruno Laganà (ORCID: https://orcid.org/0000-0003-2305-4063)
- Arianna D’Antonio (ORCID: https://orcid.org/0000-0003-1872-5299)
- Giorgio Sesti (ORCID: https://orcid.org/0000-0002-1618-7688)
- Carlo Perricone (ORCID: https://orcid.org/0000-0003-4771-6981)
- Gloria Maria Felice
- G. Crepaldi
Institutions
- University of Siena (IT)
- University of Rome Tor Vergata (IT)
- Marche Polytechnic University (IT)
- University of Udine (IT)
- University of Perugia (IT)
- Ospedale Santa Maria della Misericordia di Udine (IT)
- Ospedale Regina Margherita (IT)
- University of Turin (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Rheumatology and Therapy
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1007/s40744-024-00712-y
- Citations
- 8
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 3.76
Funders
- AbbVie