Post-Traumatic Stress Disorder and Risk of Parkinson’s Disease in a Veteran Cohort
Post-traumatic stress disorder (PTSD) may be a risk factor for Parkinson's disease (PD). We examined the relation between PTSD and PD in a cohort of 158,122 Veterans who had any Veterans Health Administration (VHA) or Medicare health care utilization between 10/1/1999- 2/17/2021. Using a nested case-control design we matched 10 controls to each Veteran with PD by sex, race, and rank. In conditional logistic regression models adjusted for camp and smoking, a PTSD diagnosis was significantly associated with PD (OR = 1.35; p = 0.0002); odds were higher if PTSD was coded before PD (OR = 1.53, p < 0.0001). PTSD may be a risk factor for PD.
Authors
- Beverly González (ORCID: https://orcid.org/0000-0002-3007-5789)
- Ethan Brown (ORCID: https://orcid.org/0000-0001-9744-8562)
- Samuel M. Goldman (ORCID: https://orcid.org/0000-0002-3039-9927)
- Frances M. Weaver (ORCID: https://orcid.org/0000-0002-5495-4649)
- Caroline M. Tanner
- Kevin T. Stroupe (ORCID: https://orcid.org/0000-0001-9735-4929)
- Lishan Cao
- Kalea Colletta (ORCID: https://orcid.org/0000-0003-0396-4481)
Institutions
- University of California, San Francisco (US)
- Loyola University Chicago (US)
- Edward Hines, Jr. VA Hospital (US)
- San Francisco VA Health Care System (US)
Publication Details
- Journal
- Journal of Parkinson s Disease
- Published
- 2024-08-20
- DOI
- https://doi.org/10.3233/jpd-240098
- Citations
- 2
- Primary Topic
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- U.S. Department of Veterans Affairs
- Centers for Disease Control and Prevention
- Agency for Toxic Substances and Disease Registry