Enhanced Brain Clearance of Tau and Amyloid-β in Alzheimer’s Disease Patients by Transcranial Radiofrequency Wave Treatment: A Central Role of Vascular Endothelial Growth Factor (VEGF)
A new mechanism of TRFT is identified (facilitation of brain tau and Aβ clearance via VEGF) that is likely contributory to TRFT's reversal of cognitive impairment in AD subjects. TRFT may be particularly effective for cognitive benefit in AD subjects who have low VEGF levels.
Authors
- Chuanhai Cao (ORCID: https://orcid.org/0000-0002-5765-6401)
- Gary W. Arendash (ORCID: https://orcid.org/0000-0003-2527-0106)
- Xiaoyang Lin
Institutions
- University of South Florida (US)
- NeuroEM Therapeutics (United States) (US)
Publication Details
- Journal
- Journal of Alzheimer s Disease
- Published
- 2024-08-20
- DOI
- https://doi.org/10.3233/jad-240600
- Citations
- 8
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 2.15
Funders
- USF Health Byrd Alzheimer's Institute
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke