Visual stimulation and brain-derived neurotrophic factor (BDNF) have protective effects in experimental autoimmune uveoretinitis
VS effectively suppresses EAU, at least through enhancing retinal levels of anti-inflammatory and neuroprotective factors, VIP and BDNF. Our findings also suggest BDNF as a promising therapeutic agent for uveitis treatment.
Authors
- Jan Hejda (ORCID: https://orcid.org/0000-0003-2461-6283)
- Patrik Kutílek (ORCID: https://orcid.org/0000-0003-4160-9851)
- Jan Kubovčiak (ORCID: https://orcid.org/0000-0001-6446-9797)
- Miloslav Zloh
- Ivana Fišerová (ORCID: https://orcid.org/0000-0002-6484-3870)
- Masaaki Murakami (ORCID: https://orcid.org/0000-0001-7544-9791)
- Andrea Štofková (ORCID: https://orcid.org/0000-0002-6579-6578)
Institutions
- National Institutes of Natural Sciences (JP)
- Hokkaido University (JP)
- Charles University (CZ)
- National Institutes for Quantum Science and Technology (JP)
- Czech Academy of Sciences, Institute of Molecular Genetics (CZ)
- National Institute for Physiological Sciences (JP)
- Czech Technical University in Prague (CZ)
Publication Details
- Journal
- Life Sciences
- Published
- 2024-08-20
- DOI
- https://doi.org/10.1016/j.lfs.2024.122996
- Citations
- 3
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 1.62
Funders
- Univerzita Karlova v Praze
- Japan Agency for Medical Research and Development
- Ministerstvo Školství, Mládeže a Tělovýchovy
- Hokkaido University
- European Regional Development Fund