Immunosuppressant Medications in Pregnancy

( Obstet Gynecol . 2024;143(4):e94–e106. doi: 10.1097/AOG,0000000000005512) Pregnant patients often take immunosuppressant medications for solid organ transplant rejection prevention or autoimmune disorders. It is important that they adhere to prescribed regimens before and during pregnancy to avoid serious consequences. Close monitoring of organ function, signs of rejection, and immunosuppressant levels are vital. Counseling for reproductive patients should include discussions on how pregnancy may impact their condition, potential fetal effects of medications, and breastfeeding considerations. This review provides detailed guidance on managing common immunosuppressants during pregnancy and lactation, along with antenatal and postpartum care timelines.