Topical Tranexamic Acid on Donor Wounds in Burn Patients: A Randomized Placebo-controlled Trial

This study demonstrates that topical application of TXA (25 mg/mL) to split-thickness skin graft donor wounds does not delay re-epithelialization. Although a reduction in bleeding is suggested, further studies are needed to determine the role of topical TXA in reducing bleeding in burn surgery.

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Publication Details

Journal
Plastic & Reconstructive Surgery Global Open
Published
2024-08-01
DOI
https://doi.org/10.1097/gox.0000000000006074
Citations
2
Primary Topic
Blood transfusion and management
Type
article
Field-Weighted Citation Impact
0.45

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article

Topical Tranexamic Acid on Donor Wounds in Burn Patients: A Randomized Placebo-controlled Trial

Stian Kreken Almeland, Olav Spigset, Kjersti Ausen, Håvard Nordgaard et al.
2 citations
Plastic & Reconstructive Surgery Global Open
Blood transfusion and management
0.45
article

Topical Tranexamic Acid on Donor Wounds in Burn Patients: A Randomized Placebo-controlled Trial

Stian Kreken Almeland, Olav Spigset, Kjersti Ausen, Håvard Nordgaard, Ragnvald Ljones L Brekke, Robert Norheim Colclough, Hilde Pleym
article en
2 citations

Abstract

This study demonstrates that topical application of TXA (25 mg/mL) to split-thickness skin graft donor wounds does not delay re-epithelialization. Although a reduction in bleeding is suggested, further studies are needed to determine the role of topical TXA in reducing bleeding in burn surgery.

Plastic & Reconstructive Surgery Global OpenVol. 12(8)
Norwegian University of Science and Technology (NO), Haukeland University Hospital (NO), St Olav's University Hospital (NO), University of Bergen (NO)
Pfizer, Norges Teknisk-Naturvitenskapelige Universitet, Helse Midt-Norge, Faculty of Medicine and Health, University of Sydney
Good health and well-being
Openalex Percentile: Top 44%
Blood transfusion and management
0.45
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