Trends in the cytogenetic and immunologic status of healthy persons; Kazakhstan, 2007–2022
Environmental pollution can affect immune health and genome stability. We have studied the immunological and cytogenetic status of healthy urban (Almaty City, which has high levels of air pollution) and rural residents of southern Kazakhstan, over the past 15 years. Differences between the groups in plasma immunoglobulin levels and chromosomal aberration frequencies were noted. Over the 15-year study period, decreases of immunoglobulin levels and increases of chromosomal aberration frequencies were observed and correlated with place of residence and ecological status of the region of residence; both ecological deterioration and the coronavirus pandemic are likely to have had negative effects.
Authors
- Unzira Kapysheva (ORCID: https://orcid.org/0000-0001-9162-5281)
- Oksana Cherednichenko (ORCID: https://orcid.org/0000-0001-5681-639X)
- Sh.K. Bakhtiyarova (ORCID: https://orcid.org/0000-0002-6434-0130)
- Bolatbek Zhaksymov
- Dinara Azizbekova (ORCID: https://orcid.org/0009-0009-4809-7212)
- Ulbosin Kozhaniyazova
- A. L. Pilyugina
- Georgij Demchenko
Institutions
- Kazakh Institute of Oncology and Radiology (KZ)
- Institute of Genetics (CA)
- Institute of Animal Physiology of the Slovak Academy of Sciences (SK)
- Czech Academy of Sciences, Institute of Physiology (CZ)
Publication Details
- Journal
- Mutation Research/Genetic Toxicology and Environmental Mutagenesis
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1016/j.mrgentox.2024.503822
- Citations
- 1
- Primary Topic
- Medical and Agricultural Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- Ministry of Education and Science of the Republic of Kazakhstan