Interval-specific likelihood ratios and probability-based models for interpreting combined CSF biomarkers for Alzheimer’s disease
Interval-specific LRs in a combined biomarker model and prediction of AD using a continuous bivariate biomarker probability-based model, offer a more meaningful interpretation of CSF AD biomarkers on a (semi-)continuous scale with respect to the post-test probability of AD across different assays and cohorts.
Authors
- Koen Poesen (ORCID: https://orcid.org/0000-0001-5290-9476)
- Jonas Dubin (ORCID: https://orcid.org/0009-0004-4882-2481)
- Rik R. Vandenberghe (ORCID: https://orcid.org/0000-0001-6237-2502)
Institutions
- Universitair Ziekenhuis Leuven (BE)
- VIB-KU Leuven Center for Brain & Disease Research (BE)
- KU Leuven (BE)
Publication Details
- Journal
- Clinica Chimica Acta
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1016/j.cca.2024.119941
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00