Pregestational Maternal Risk Factors for Preterm and Term Preeclampsia: A Population-based Cohort Study

( Acta Obstet Gynecol Scand . 2023;102(11):1549-1557. doi: 10.1111/aogs.14642) Preeclampsia represents a large proportion of global maternal and neonatal morbidity and mortality. Through evidence and careful study, it has been classified into preterm and term preeclampsia, but few population-based studies have made this distinction in diagnosis. The only curative treatment for preeclampsia is delivery, and all other treatments known for this disease are preventive. In addition to differences in timing and presentation, preterm preeclampsia has several risk factors that do not apply to individuals with term preeclampsia, such as chronic hypertension, type 1 diabetes, and maternal allergy. This study was designed to assess the associations of prepregnancy conditions (diabetes types 1 and 2, chronic kidney disease, asthma, epilepsy, rheumatoid arthritis, and chronic hypertension) with preterm versus term preeclampsia at a population level.