Effects of a 217‐km mountain ultramarathon on the gut microbiota of an obese runner: A case report

Obesity is characterized by specific changes in the composition of the gut microbiota (GM). Exercise can contribute to the modulation of GM. This is the first case study to analyze the composition and metabolism of the GM of an obese runner in a single-stage mountain ultramarathon (MUM) with a mileage of 217 km. Fecal samples were collected 7 days before the race (T0), 15 min after the end of the race (T1), and 7 days after the end of the race (T2). GM composition was analyzed by real-time PCR and shotgun sequencing. We observed a decrease in Bacillota/Bacteroidota ratio and α-diversity after the race. After the 217-km MUM, we observed a decrease in symbiont microorganisms and a notable increase in harmful bacteria. In conclusion, we found that the 217-km MUM may have contributed to the intestinal dysbiosis of the obese runner.

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Publication Details

Journal
Physiological Reports
Published
2024-08-01
DOI
https://doi.org/10.14814/phy2.70017
Citations
4
Primary Topic
Exercise and Physiological Responses
Type
article
Field-Weighted Citation Impact
1.00

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article

Effects of a 217‐km mountain ultramarathon on the gut microbiota of an obese runner: A case report

Luiz Felipe Valter de Oliveira, Kátia Sivieri, Adilson Sartoratto, Nayara Kastem Scharlack et al.
4 citations
Physiological Reports
Exercise and Physiological Responses
1.00
article

Effects of a 217‐km mountain ultramarathon on the gut microbiota of an obese runner: A case report

Luiz Felipe Valter de Oliveira, Kátia Sivieri, Adilson Sartoratto, Nayara Kastem Scharlack, Fernando Moreira Simabuco, Adriane Elisabete Costa Antunes, Taísa Belli, Giulio Kai Saragiotto, Milena Merizzi de Oliveira, Fernanda Campos Freire
article en
4 citations

Abstract

Obesity is characterized by specific changes in the composition of the gut microbiota (GM). Exercise can contribute to the modulation of GM. This is the first case study to analyze the composition and metabolism of the GM of an obese runner in a single-stage mountain ultramarathon (MUM) with a mileage of 217 km. Fecal samples were collected 7 days before the race (T0), 15 min after the end of the race (T1), and 7 days after the end of the race (T2). GM composition was analyzed by real-time PCR and shotgun sequencing. We observed a decrease in Bacillota/Bacteroidota ratio and α-diversity after the race. After the 217-km MUM, we observed a decrease in symbiont microorganisms and a notable increase in harmful bacteria. In conclusion, we found that the 217-km MUM may have contributed to the intestinal dysbiosis of the obese runner.

Physiological ReportsVol. 12(16)
Universidade de São Paulo (BR), Universidade Estadual de Campinas (UNICAMP) (BR), Universidade Estadual Paulista (Unesp) (BR), Universidade Federal de São Paulo (BR)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Universidade Estadual de Campinas, Fundo de Apoio ao Ensino, à Pesquisa e Extensão, Universidade Estadual de Campinas
Openalex Percentile: Top 21%
Exercise and Physiological Responses
1.00
DOIOpen Access PDFOpenAlex
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