Exploring the causal association between epigenetic clocks and menopause age: insights from a bidirectional Mendelian randomization study
The observed increase in granulocyte DNAm levels in relation to menopausal age could potentially serve as a valuable indicator for evaluating the physiological status at the onset of menopause.
Authors
- Chunyan Hou (ORCID: https://orcid.org/0000-0001-5966-1899)
- Meihua Bao (ORCID: https://orcid.org/0000-0003-4784-7076)
- Binsheng He (ORCID: https://orcid.org/0000-0002-2232-4634)
- Xiaoju Men
- Rumeng Chen (ORCID: https://orcid.org/0000-0001-7258-3100)
- Lingling Wang (ORCID: https://orcid.org/0000-0003-0272-2974)
- Sen Li (ORCID: https://orcid.org/0000-0003-4496-5050)
- Zhu Wu
- Menghua Liu (ORCID: https://orcid.org/0000-0001-5961-2202)
- Yining Ding
- Shuling Xu
Institutions
- Changsha Medical University (CN)
- Beijing University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-08-23
- DOI
- https://doi.org/10.3389/fendo.2024.1429514
- Citations
- 7
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.64
Funders
- National Natural Science Foundation of China
- Scientific Research Foundation of Hunan Provincial Education Department