Transcriptome analysis to explore the mechanism of downregulated TNIK influencing the effect of risperidone
The study indicated that risperidone primarily influences functions and/or pathways associated with bone metabolism, potentially contributing to the adverse effect of osteoporosis. Our study may offer a novel perspective on investigating the mechanisms underlying the adverse effects of risperidone.
Authors
- Yingmei Fu (ORCID: https://orcid.org/0000-0002-2526-6257)
- Ailing Ning
- Qingqing Xu (ORCID: https://orcid.org/0000-0002-7703-5872)
- Dongxiang Wang (ORCID: https://orcid.org/0000-0002-3189-0160)
- Yaojing Li
- Shunying Yu (ORCID: https://orcid.org/0000-0001-7929-204X)
- Ran Zhang (ORCID: https://orcid.org/0000-0002-0921-078X)
- Ruixue Yuan (ORCID: https://orcid.org/0000-0003-2436-4063)
- Xiangyi Li
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai Mental Health Center (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-08-23
- DOI
- https://doi.org/10.3389/fphar.2024.1431923
- Primary Topic
- Protein Kinase Regulation and GTPase Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Fundamental Research Funds for the Central Universities