Effects of the ACE2-Ang-(1-7)-Mas axis on gut flora diversity and intestinal metabolites in SuHx mice
The findings suggest that modulation of the ACE2-Ang-(1-7)-Mas axis can alleviate PAH by regulating intestinal microbes and metabolites. These results highlight the potential of the ACE2-Ang-(1-7)-Mas axis as a promising therapeutic target for clinical management of PAH.
Authors
- Tao Yang (ORCID: https://orcid.org/0000-0002-4182-9793)
- Lei Fang (ORCID: https://orcid.org/0000-0003-2510-1281)
- Yiliyaer Nijiati
- Adilai Aihemaitituoheti
- Yupeng Zhang (ORCID: https://orcid.org/0000-0002-6058-8702)
- Daliya Shanahaiti
- Ainiwaer Aikemu
- Asimuguli Abudukeremu
Institutions
- Xinjiang Medical University (CN)
- Xinjiang Institute of Engineering (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2024-08-23
- DOI
- https://doi.org/10.3389/fmicb.2024.1412502
- Citations
- 3
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.26
Funders
- National Natural Science Foundation of China