Enhanced anti-inflammatory activity of chlorogenic acid via folic acid-TPGS-modified liposomes encapsulation: characterization and In vivo evaluation on colitis mice
Following encapsulation of CGA within liposomes, FTCLP revealed favorable stability and sustained release properties, and enhanced the anti-inflammatory effects by modulating multiple inflammation-related biomarkers. FTCLP has the potential to be a safe and effective drug for targeted therapy of colitis.
Authors
- Zhou Zhi-e
- Jiahui Yan (ORCID: https://orcid.org/0000-0003-1593-460X)
- Jianhua Xiong (ORCID: https://orcid.org/0000-0002-9261-0660)
- Xiang Geng (ORCID: https://orcid.org/0000-0002-3697-6713)
- Qing-qing Li
Institutions
- Agricultural Product Processing Research Institute (CN)
- Jiangxi Agricultural University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-08-23
- DOI
- https://doi.org/10.3389/fphar.2024.1437773
- Citations
- 7
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.64
Funders
- National Natural Science Foundation of China