LncRNA ILF3AS1, MMP3, and MMP9 as well as miRNA-212 as emerging novel biomarkers for childhood epilepsy
Serum levels of the lncRNA ILF3AS1 among children with epilepsy were higher than those in the control group and were associated with upregulation of both MMP3 and MMP9 as well as downregulation of miRNA-212 expressions, suggesting their predictive utility in monitoring the development of epilepsy; this also means that a treatment plan focusing on the ILF3AS1/miRNA-212/MMP3/MMP9 axis could be an effective strategy for treating epilepsy.
Authors
- Rasha Sobhy Elattar
- Aya Ghamry
- Aliaa A. Mosa
- Marwa A. Dahpy (ORCID: https://orcid.org/0000-0002-6007-5691)
- Alshaymaa A. Abd Elalim
- Marwa A. Sabet (ORCID: https://orcid.org/0000-0001-9557-1153)
- Marwa G. Gamea (ORCID: https://orcid.org/0000-0001-9747-5253)
- Marwa K. Khairallah (ORCID: https://orcid.org/0000-0001-5226-0056)
- Salwa Seif Eldin
- Wafaa Emam (ORCID: https://orcid.org/0000-0003-2148-6444)
- Amena Rezk Mohammed (ORCID: https://orcid.org/0000-0001-8876-0925)
- Haidy Mahmoud Nasr
- Yasser G. Abish
- Sabah M. Alkhawagah
- Boshra Ahmed Zaghloul
- Amal Fahmy Dawood
- Doaa Sadek Ahmed Fathy
- Shaymaa A. Mohammed
- Suzan Eid Elshishtawy Ibrahim
- Abdullah Hussein
- Norah Alharbi
- Eatemad Nabil Mansour
Institutions
- Princess Nourah bint Abdulrahman University (SA)
- Ain Shams University (EG)
- Al-Azhar University (EG)
- Armed Forces College of Medicine (EG)
- Sphinx University (EG)
- Assiut University (EG)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2024-08-23
- DOI
- https://doi.org/10.3389/fmolb.2024.1434023
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00