Association of Seizure Control With Cognition in People With Normal Cognition and Mild Cognitive Impairment
In this study, active seizures but not remote seizures were associated with earlier cognitive decline in both cognitively normal adults and those with MCI, independent of other dementia risk factors. Therefore, early identification and management of seizures may present a path to mitigation of cognitive decline in the aging epileptic population. A limitation is that causality cannot be confirmed in our observational longitudinal study.
Authors
- Ifrah Zawar (ORCID: https://orcid.org/0000-0002-6103-4250)
- Chad Aldridge (ORCID: https://orcid.org/0000-0003-0539-9762)
- Mark Quigg (ORCID: https://orcid.org/0000-0003-3035-9260)
- Meghan Mattos (ORCID: https://orcid.org/0000-0001-7355-7190)
- Carol A. Manning (ORCID: https://orcid.org/0000-0003-4205-2485)
- Jaideep Kapur (ORCID: https://orcid.org/0000-0002-8608-1352)
Institutions
- University of Virginia (US)
Publication Details
- Journal
- Neurology
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1212/wnl.0000000000209820
- Citations
- 25
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 9.64
Funders
- Epilepsy Society
- National Institutes of Health
- National Institute on Aging