Ginsenoside Rg3 targets glycosylation of PD-L1 to enhance anti-tumor immunity in non-small cell lung cancer

These results suggest that Rg3 inhibits PD-L1 glycosylation and thus enhance anti-tumor immunity, which provide new therapeutic insight into drug discovery.

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Publication Details

Journal
Frontiers in Immunology
Published
2024-08-23
DOI
https://doi.org/10.3389/fimmu.2024.1434078
Citations
17
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
4.09
Controls
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article

Ginsenoside Rg3 targets glycosylation of PD-L1 to enhance anti-tumor immunity in non-small cell lung cancer

Min Kong, Fu Shen, Weichun Li, Wei Wang et al.
17 citations
Frontiers in Immunology
Immune Cell Function and Interaction
4.09
article

Ginsenoside Rg3 targets glycosylation of PD-L1 to enhance anti-tumor immunity in non-small cell lung cancer

Min Kong, Fu Shen, Weichun Li, Wei Wang, Cheng Chen, Ping Li, Cheng Li, Liang Yang, Aihua Zhong, Zhiqiang Qian, Yuhua Wang, Yueqin Li, Fangkai He
article en
17 citations

Abstract

These results suggest that Rg3 inhibits PD-L1 glycosylation and thus enhance anti-tumor immunity, which provide new therapeutic insight into drug discovery.

Frontiers in ImmunologyVol. 15
Nanjing University of Chinese Medicine (CN), Second Military Medical University (CN), Nantong University (CN), Shanghai University of Traditional Chinese Medicine (CN), Jiangning District of Nanjing Chinese Medicine Hospital (CN), Changhai Hospital (CN), The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN), Traditional Chinese Medicine Hospital of Kunshan (CN), Nanjing Medical University (CN)
Good health and well-being
Openalex Percentile: Top 5%
Immune Cell Function and Interaction
4.09
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