HMGB2 drives tumor progression and shapes the immunosuppressive microenvironment in hepatocellular carcinoma: insights from multi-omics analysis
HMGB2 emerges as a critical player of HCC progression, metastasis, and immunosuppression. Its elevated expression correlates with aggressive tumor behavior and poor patient outcomes, suggesting its potential as both a therapeutic target and a prognostic indicator in HCC management.
Authors
- Zhishang Meng
- Zuo‐Lin Xiang (ORCID: https://orcid.org/0000-0002-5725-842X)
- Yanzhu Chen (ORCID: https://orcid.org/0000-0001-5589-9197)
Institutions
- Central South University (CN)
- Shanghai East Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-08-23
- DOI
- https://doi.org/10.3389/fimmu.2024.1415435
- Citations
- 11
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 2.83