Impact of primary tumor sidedness and sex on prognosis and anti-epidermal growth factor receptor antibody efficacy in BRAF-mutant metastatic colorectal cancer: a pooled analysis of AIO studies FIRE-1, CIOX, FIRE-3, XELAVIRI, and VOLFI
This analysis suggests that PTS has predictive value for the efficacy of anti-EGFR mAb in the first-line treatment of BRAFmt mCRC.
Authors
- T Decker
- Clemens Gießen-Jung (ORCID: https://orcid.org/0000-0003-0537-1727)
- Lena Weiss (ORCID: https://orcid.org/0000-0002-8101-3529)
- Arndt Stahler (ORCID: https://orcid.org/0000-0003-1041-0137)
- Sebastian Stintzing (ORCID: https://orcid.org/0000-0002-3297-5801)
- Volker Heinemann (ORCID: https://orcid.org/0000-0002-1349-3321)
- Ursula Vehling‐Kaiser
- Dominik Paul Modest (ORCID: https://orcid.org/0000-0002-6853-0599)
- Annabel Helga Sophie Alig (ORCID: https://orcid.org/0000-0002-3922-3450)
- Andrea Tannapfel (ORCID: https://orcid.org/0000-0002-0711-7100)
- Swantje Held (ORCID: https://orcid.org/0000-0002-1344-9056)
- Michael Geißler (ORCID: https://orcid.org/0000-0003-0265-8490)
- Andreas Jung (ORCID: https://orcid.org/0000-0001-5270-9108)
- Kathrin Heinrich (ORCID: https://orcid.org/0000-0003-3580-2313)
- Nicolas Moosmann
- Ludwig Fischer von Weikersthal (ORCID: https://orcid.org/0000-0002-9128-0807)
Institutions
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Humboldt-Universität zu Berlin (DE)
- Comprehensive Cancer Center Vienna (AT)
- Krankenhaus Barmherzige Brüder (DE)
- ClinAssess (Germany) (DE)
- Klinikum St. Marien Amberg (DE)
- Ludwig-Maximilians-Universität München (DE)
- Ruhr University Bochum (DE)
Publication Details
- Journal
- ESMO Open
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1016/j.esmoop.2024.103677
- Citations
- 6
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.70
Funders
- Pfizer